Posts Tagged ‘University of Manchester’

‘I’ Article About Research into Artificial Wombs and their Morality

January 8, 2020

This is another science story from yesterday’s I for 7th January 2020. It’s about current research into developing artificial wombs. At the moment, these would be for very premature babies, but they could in theory go much further, which raises some serious ethical issues.

The article by Alla Katsnelson, ‘Baby in a bag: could humans be grown in an artificial womb?’ runs

Critically preterm babies face an uncertain future. Although a foetus is considered viable at 24 weeks of gestation, only about 60 per cent of babies born so young will survive, and many will experience life-long complications.

For those born a couple of weeks earlier, the statistics are even more dire: just 10 per cent of babies born at 22 weeks are likely to survive.

building a so-called artificial womb could potentially save these babies. In October, researchers from Eindhoven University of Technology in the Netherlands announced that they had received a grant for E2.9m (£2.5m) to develop a prototype of such a device. But the project isn’t the only artificial womb on the horizon. In 2017, researchers in Philadelphia transferred foetal lambs, aged between 105 and 115 days of gestation (equivalent to about 28 to 30 weeks human gestation), into a so-called biobag filled with artificial amniotic fluid. After several weeks in the bag, the lambs developed normally. And in March 2019, an Australian and Japanese research team kept younger lambs, about 95 days’ gestational age, alive in a different system.

Dr Matthew Kemp, who led the latter work, admits that researchers don’t fully understand foetal growth in the womb, which makes replicating it a challenge. The Dutch group noted plans to roll out a clinic-ready prototype in five years, but Dr Kemp says it will probably take much longer. And because the technology is so costly, it’s unlikely to be widely available any time soon.

So far, what researchers call artificial wombs are essentially souped-up incubators. They provide a fluid-filled space in which a foetus can receive nutrients and oxygen through a ‘placenta’. From there to full-on ectogenesis – incubating foetuses outside a human for the full duration of a pregnancy – is an enormous leap.

But many bioethicists note that technology moves quickly, and proactively thinking through the possibilities is important.

In this more futuristic vision, artificial wombs can do a lot for society, says Dr Elizabeth Yuko, a bioethicist at Fordham University in New York. It could allow people who can’t carry a pregnancy for whatever reason – illness, infertility, age, or gender – to do so. It might also shift some of the childbearing responsibilities carried by women. But it also raises concerns. For example, ex-utero gestation would probably turn reproductive rights on their head, says Elizabeth Chloe Romanis, a lawyer and bioethicist at the University of Manchester. If a foetus can gestate outside a woman’s body, the choice fo whether or not to have the baby might be deemed out of her hands.

Another issue is that our legal rights are predicated on having been born alive. “I don’t think that a gestating subject in an artificial womb necessarily meets that requirement,” says Romanis. “That raises some questions about human entities ex-utero that have never existed before.

There have been newspaper articles about the development of artificial wombs since the 1980s, at least. The Absurder published one c. 1985, and I think the Independent also published one in the 1990s. And the whole area of artificial reproduction has been a live issue since the first ‘test tube’ baby created through in vitro fertilisation in the 1970s. But it also raises the spectacle of the kind of dystopian society Aldous Huxley portrayed in Brave New World, where humans are bred in hatcheries, engineered and conditioned for their future role in society. The Auronar, the telepathic race to which Cally, one of the heroes of the Beeb’s SF series, Blake’s 7, also reproduced through artificial gestation.And one of the predictions in Brian Stableford’s and David Langford’s future history, The Third Millennium, is that during this millennium this will be the preferred method of human reproduction, at least in some extraterrestrial colonies. And over a decade Radio 4 broadcast a series in which various intellectuals created fictional museums. One was ‘the museum of the biological body’, set in a post-human future in which people were neuter cyborgs born from hatcheries. This is obviously very far off, and I doubt anywhere near the majority of humans would ever want to reject gender and sexuality completely, whatever certain sections of the trans community might believe.

As with cloning and Dolly the Sheep, it raises very profound and disturbing questions about humanity’s future and how far technology should expand into the area of reproduction.